A selective thioxothiazolidin-coumarin probe for Hg2+ based on its desulfurization reaction. Exploring its potential for live cell imaging

Margarita E. Aliaga, Marcela Gazitua, Andrea Rojas-Bolaños, Marcial Fuentes-Estrada, Diego Durango, Olimpo García-Beltrán

Resultado de la investigación: Contribución a una revistaArtículo

1 Cita (Scopus)

Resumen

Sensing the most toxic heavy metal (mercury) has attracted a lot of attention in recent years due to its extreme harmfulness to both human health and the environment. Thus, we reported herein the synthesis, spectroscopic and kinetic characterization, and biological evaluation of a new thioxothiazolidin coumarin derivative (ILA92), which undergoes a desulfurization reaction induced by mercuric ions (Hg2+). This process is the origin of a selective sensing of Hg2+ ions in aqueous solution by colorimetric and fluorescent methods. Furthermore, the probe showed great potential for imaging Hg2+ in living cells.

Idioma originalInglés
Número de artículo117372
PublicaciónSpectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy
Volumen224
DOI
EstadoPublicada - 5 ene 2020

Huella dactilar

Desulfurization
Ions
Imaging techniques
Coumarins
Mercury (metal)
Poisons
Heavy Metals
Mercury
Heavy metals
Cells
Health
Derivatives
Kinetics
coumarin

Citar esto

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title = "A selective thioxothiazolidin-coumarin probe for Hg2+ based on its desulfurization reaction. Exploring its potential for live cell imaging",
abstract = "Sensing the most toxic heavy metal (mercury) has attracted a lot of attention in recent years due to its extreme harmfulness to both human health and the environment. Thus, we reported herein the synthesis, spectroscopic and kinetic characterization, and biological evaluation of a new thioxothiazolidin coumarin derivative (ILA92), which undergoes a desulfurization reaction induced by mercuric ions (Hg2+). This process is the origin of a selective sensing of Hg2+ ions in aqueous solution by colorimetric and fluorescent methods. Furthermore, the probe showed great potential for imaging Hg2+ in living cells.",
keywords = "Colorimetric fluorescent dye, Desulfurization reaction, Hg ions, Naked eye sensor, Thioxothiazolidin coumarin derivative",
author = "Aliaga, {Margarita E.} and Marcela Gazitua and Andrea Rojas-Bola{\~n}os and Marcial Fuentes-Estrada and Diego Durango and Olimpo Garc{\'i}a-Beltr{\'a}n",
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A selective thioxothiazolidin-coumarin probe for Hg2+ based on its desulfurization reaction. Exploring its potential for live cell imaging. / Aliaga, Margarita E.; Gazitua, Marcela; Rojas-Bolaños, Andrea; Fuentes-Estrada, Marcial; Durango, Diego; García-Beltrán, Olimpo.

En: Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, Vol. 224, 117372, 05.01.2020.

Resultado de la investigación: Contribución a una revistaArtículo

TY - JOUR

T1 - A selective thioxothiazolidin-coumarin probe for Hg2+ based on its desulfurization reaction. Exploring its potential for live cell imaging

AU - Aliaga, Margarita E.

AU - Gazitua, Marcela

AU - Rojas-Bolaños, Andrea

AU - Fuentes-Estrada, Marcial

AU - Durango, Diego

AU - García-Beltrán, Olimpo

PY - 2020/1/5

Y1 - 2020/1/5

N2 - Sensing the most toxic heavy metal (mercury) has attracted a lot of attention in recent years due to its extreme harmfulness to both human health and the environment. Thus, we reported herein the synthesis, spectroscopic and kinetic characterization, and biological evaluation of a new thioxothiazolidin coumarin derivative (ILA92), which undergoes a desulfurization reaction induced by mercuric ions (Hg2+). This process is the origin of a selective sensing of Hg2+ ions in aqueous solution by colorimetric and fluorescent methods. Furthermore, the probe showed great potential for imaging Hg2+ in living cells.

AB - Sensing the most toxic heavy metal (mercury) has attracted a lot of attention in recent years due to its extreme harmfulness to both human health and the environment. Thus, we reported herein the synthesis, spectroscopic and kinetic characterization, and biological evaluation of a new thioxothiazolidin coumarin derivative (ILA92), which undergoes a desulfurization reaction induced by mercuric ions (Hg2+). This process is the origin of a selective sensing of Hg2+ ions in aqueous solution by colorimetric and fluorescent methods. Furthermore, the probe showed great potential for imaging Hg2+ in living cells.

KW - Colorimetric fluorescent dye

KW - Desulfurization reaction

KW - Hg ions

KW - Naked eye sensor

KW - Thioxothiazolidin coumarin derivative

UR - http://www.scopus.com/inward/record.url?scp=85069695523&partnerID=8YFLogxK

U2 - 10.1016/j.saa.2019.117372

DO - 10.1016/j.saa.2019.117372

M3 - Artículo

AN - SCOPUS:85069695523

VL - 224

JO - Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy

JF - Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy

SN - 1386-1425

M1 - 117372

ER -